Biovision
Human CellExp™ IL-1α, Human Recombinant
- SKU:
- 26-P1717
- UPC:
- MPN:
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 20 µg
- Storage Temperature:
- -20ºC
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: N/A
Synonyms: Interleukin-1 alpha; Hematopoietin-1; IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
Alternates names: N/A
Taglines: Critical mediator of inflammatory response
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 3552
NCBI Gene Symbol: N/A
Gene Source: Human
Accession #: P01583
Recombinant: True
Source: HEK 293 cells
Purity by SDS-PAGE #: ≥ 95% by SDS-PAGE
Assay: N/A
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1 EU per 1 µg of protein as determined by LAL method
Activity (Specifications/test method): N/A
Biological activity: Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells (ED50 typically 0.2-1 ng/mL) and by its ability to induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells (ED50 typically 0.07-0.35 µg/mL)
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 18 kDa calculated; 22 kDa observed
Concentration: N/A
Appearance: Liquid protein
Physical form description: Lyophilized powder
Reconstitution Instructions: N/A
Background Information: Interleukin-1 (IL-1) is produced by activated macrophages and stimulates thymocyte proliferation by inducing IL-2 release. IL-1 also induces B-cell maturation and proliferation, and modulates fibroblast growth factor activity. IL-1 proteins have been identified as endogenous pyrogens, and are involved in the inflammatory response.
Amino acid sequence: Ser 113 to Ala 271 of human IL-1α
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
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