Human CellExp™ IL-2, Human Recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- gel pack
- Shelf Life:
- 12 months
Synonyms: Human Cellexp Human Recombinant IL-2
Alternates names: T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2.
Taglines: A regulator of lymphocyte activities
Country of Animal Origin: USA
NCBI Gene ID #.: 3558
NCBI Gene Symbol: IL2
Gene Source: Human
Accession #: P60568
Source: Human 293 cell expressed
Purity by SDS-PAGE #: ≥95%
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 μg of protein
Activity (Specifications/test method): N/A
Biological activity: ED₅is typically 0.2 to 2 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell line).
Results: 0.2 to 2 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 15 kDa, monomer, glycosylated
Physical form description: Lyophilized from a PBS solution.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Background Information: IL-2 is a potent immuno-modulator, which mediates a wide range of immune and inflammatory responses and is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans