Biovision
Human CellExp™ NOV, human recombinant
- SKU:
- 26-P1022
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: NOV
Synonyms: Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
Alternates names: Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
Taglines: N/A
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 4856
NCBI Gene Symbol: NOV
Gene Source: Human
Accession #: P48745
Recombinant: Yes
Source: CHO cells
Purity by SDS-PAGE #: > 95%
Assay: SDS-PAGE
Purity: > 95%
Assay #2: HPLC
Endotoxin Level: < 0.2 EU/μg
Activity (Specifications/test method): Prolifiration assay
Biological activity: ED50 <5 μg/ml, measured in a cell proliferation assay using 3T3 cells.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 20-50 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized after extensive dialysis against PBS.
Reconstitution Instructions: Reconstituted in ddH2O at 100 μg/mL.
Background Information: Nephroblastoma Overexpressed Gene Protein (NOV), also known as CCN3, IGFBP9 and NOVH, is one of the CCN family of secreted proteins. It is expressed in bone marrow, thymic cells and nephroblastoma. NOV signals through integrin receptors, NOTCH1 and fibulin 1c to regulate multiple cellular activities, such as cell adhesion, migration, proliferation and differentiation. The reported functions of NOV are diverse. It has been reported to play a role in angiogenesis and stem cell self-renewal. It has also been implicated in osteogenic differentiation, embryo development and cancer pathogenesis.
Amino acid sequence: TQRCPPQCPG RCPATPPTCA PGVRAVLDGC SCCLVCARQR GESCSDLEPC DESSGLYCDR SADPSNQTGI CTAVEGDNCV FDGVIYRSGE KFQPSCKFQC TCRDGQIGCV PRCQLDVLLP EPNCPAPRKV EVPGECCEKW ICGPDEEDSL GGLTLAAYRP EATLGVEVSD SSVNCIEQTT EWTACSKSCG MGFSTRVTNR NRQCEMLKQT RLCMVRPCEQ EPEQPTDKKG KKCLRTKKSL KAIHLQFKNC TSLHTYKPRF CGVCSDGRCC TPHNTKTIQA EFQCSPGQIV KKPVMVIGTC TCHTNCPKNN EAFLQELELK TTRGKM
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans