Human CellExp™ Prolactin, Human Recombinant

Biomolecule/Target: Prolactin

Synonyms: prolactin, PRL, GHA1, luteotropin

Alternates names: prolactin, PRL, GHA1, luteotropin

Taglines: An important regulator of immune system with cell cycle related functions

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 5617

NCBI Gene Symbol: PRL

Gene Source: Human

Accession #: P01236

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: ≥95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 24 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered PBS (pH 7.4) with 5% trehalose

Reconstitution Instructions: Reconstitute in sterile PBS (pH 7.4)

Background Information: Prolactin is a hormone that is mainly secreted by lactotroph cells of the anterior pituitary gland. It is involved in many biological processes including lactation, metabolism, regulation of the immune system and reproduction. The major isoform acts via its membrane receptor, the prolactin receptor (PRL-R), which is a member of the haematopoietic cytokine superfamily. One of the prolactin isoforms has received particular attention as a result of its recently discovered inhibitory effects on angiogenesis and tumorigenesis. The discovery of multiple extrapituitary sites of prolactin secretion also increases the range of known functions of this hormone. Prolactin and its receptor serve multiple physiological and pathological roles in human pathophysiology.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans