Human CellExp™ TGF-beta 1, Human Recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- gel pack
- Shelf Life:
- 12 months
Synonyms: Human Cellexp Human Recombinant TGF-beta 1
Alternates names: Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, LAP, TGFB1.
Taglines: A protein that controls proliferation, cellular differentiation, & other functions in most cells
Country of Animal Origin: China
NCBI Gene ID #.: 7040
NCBI Gene Symbol: TGFB1
Gene Source: Human
Accession #: P01137
Source: Human 293 cell expressed
Purity by SDS-PAGE #: > 95%
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 μg of protein
Activity (Specifications/test method): N/A
Biological activity: ED₅₀ is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
Results: 0.1 to 0.5 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 25 kDa, homodimer, nonglycosylated
Physical form description: Lyophilized from 50 mM sodium acetate, pH 4.5 and 350 mM NaCl.
Reconstitution Instructions: Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin.
Background Information: Transforming growth factor betas (TGFβ) mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-beta 1 is involved in hematopoiesis and endothelial differentiation.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans