OryzaExp™ Alpha-1 Antitrypsin, Human Recombinant

Biomolecule/Target: N/A

Synonyms: Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, AAT, PI

Alternates names: Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, AAT, PI

Taglines: An acute-phase plasma protein

Taglines: USA

Country of Animal Origin: N/A

NCBI Gene ID #.: 5265

NCBI Gene Symbol: SERPINA1

Gene Source: Human

Accession #: AAB59375

Recombinant: True

Source: Orzya sativa

Purity by SDS-PAGE #: > 95%

Assay: N/A

Purity: N/A

Assay #2: N/A

Endotoxin Level: ≤1EU/ug

Activity (Specifications/test method): 3~5 mg OsrAAT inhibit 1 mg PPE (pancreatic porcine elastase) with 10.8 units per mg protein.

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 43.2 KDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Lyophilized

Reconstitution Instructions: Reconstitute in sterile PBS

Background Information: Alpha 1 Antitrypsin is an acute-phase plasma protein found at 290 mg per 100 ml. It functions as a serine protease inhibitor with targets like elastase, plasmin, collagenase, thrombin, leucocyte proteases, trypsin, chymotrypsin, and plasminogen activator. Clinically, its deficiency is associated with two major diseases: pulmonary emphysema and early onset/juvenile hepatic cirrhosis. It is elevated in inflammatory conditions, malignancies, liver disease and pregnancy and also after surgical trauma and use of oral contraceptives. The simultaneous quantitative determination of alpha-1-PI and ceruloplasmin permits differential diagnosis of liver afflictions. Rise in alpha 1 antitrypsin occurs as an acute phase response to tissue necrosis and inflammatio

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: N/A