EZSolution™ Calpain Inhibitor, Z-LLY-FMK

A potent, cell-permeable, and irreversible inhibitor of calpain II (k₂ = 28,900 M⁻¹s⁻¹). Also acts as an inhibitor of cathepsin L (k₂= 680,000 M⁻¹s⁻¹).

Alternate Name/Synonyms: Z-LLY-FMK, Calpain Inhibitor(fluoromethylketone)

Appearance: Liquid

Appearance: DMSO (10 mM)

Appearance: 133410-84-1

Appearance: No

Peptide sequence: Z-Leu-Leu-Tyr-FMK

Salt Form: No

Molecular Formula: C₃₀H₄₀FN₃O₆

Molecular Weight: 557.7

Cell-Permeable?: Yes

Purity: >95% by HPLC

Solubilities: N/A

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A cathepsin B & L and Calpain inhibitor

MDL Number: N/A

PubChem CID: 16760337

SMILES: CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)CF)NC(=O)C(CC(C)C)NC(=O)OCC2=CC=CC=C2

InChi: InChI=1S/C30H40FN3O6/c1-19(2)14-25(28(37)32-24(27(36)17-31)16-21-10-12- 23(35)13-11-21)33-29(38)26(15-20(3)4)34-30(39)40-18-22-8-6-5-7-9-22/h5- 13,19-20,24-26,35H,14-18H2,1-4H3,(H,32,37)(H,33,38)(H,34,39)

InChi Key: JCRSHQCFRMCMOC-UHFFFAOYSA-N

Category: Calpain