EZSolution™ Stat3 Inhibitor I, S3I-201

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SKU:
26-2541
Availability:
Usually Shipped in 5 Working Days
Size:
5 mg
Storage Condition:
-20°C
Shipping Condition:
gel pack
Shelf Life:
12months
€160.00
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Description

Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and inhibits the growth of human breast tumors in vivo.

Alternate Name/Synonyms: 2-Hydroxy-4-[[[[4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid; NSC 74859; S3I-201

Appearance: Liquid

Appearance: A 10 mM solution in anhydrous DMSO

Appearance: 501919-59-1

Appearance: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₅NO₇S

Molecular Weight: 365.36

Cell-Permeable?: Yes

Purity: ≥97% by HPLC

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A Stat3 Inhibitor

MDL Number: MFCD09907564

PubChem CID: 252682

SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O

InChi: InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)

InChi Key: HWNUSGNZBAISFM-UHFFFAOYSA-N

Category: Biochemicals

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