Biovision
EZSolution™ Stat3 Inhibitor I, S3I-201
- SKU:
- 26-2541
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 5 mg
- Storage Condition:
- -20°C
- Shipping Condition:
- gel pack
- Shelf Life:
- 12months
Description
Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and inhibits the growth of human breast tumors in vivo.
Alternate Name/Synonyms: 2-Hydroxy-4-[[[[4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid; NSC 74859; S3I-201
Appearance: Liquid
Appearance: A 10 mM solution in anhydrous DMSO
Appearance: 501919-59-1
Appearance: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₅NO₇S
Molecular Weight: 365.36
Cell-Permeable?: Yes
Purity: ≥97% by HPLC
Solubilities: N/A
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A Stat3 Inhibitor
MDL Number: MFCD09907564
PubChem CID: 252682
SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O
InChi: InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)
InChi Key: HWNUSGNZBAISFM-UHFFFAOYSA-N
Category: Biochemicals