Human CellExp™ ABP1/AOC1, Human Recombinant

Biomolecule/Target: N/A

Synonyms: Amiloride-sensitive amine oxidase, DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, ABP, ABP1, DAO1

Alternates names: Amiloride-sensitive amine oxidase, DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, ABP, ABP1, DAO1

Taglines: Catalyzes the oxidation of biogenic amines

Taglines: USA

Country of Animal Origin: N/A

NCBI Gene ID #.: 26

NCBI Gene Symbol: AOC1

Gene Source: Human

Accession #: P19801

Recombinant: TRUE

Source: HEK 293 cells

Purity by SDS-PAGE #: >90%

Assay: SDS - PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 84.2 kDa (6 x His tag at C terminal)

Concentration: N/A

Appearance: Sterile Filtered colorless solution

Physical form description: Liquid

Reconstitution Instructions: N/A

Background Information: ABP1, also known as diamine oxidase (DAO) and amine oxidase copper domain-containing protein 1 (AOC1), is a member of the copper-containing amine oxidase family. This enzyme catalyzes the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. It has an important role in the catabolism of histamine and other bioactive polyamines. Deficiencies in ABP1 can result in histaminosis or dietary histamine intolerance. This protein is also contributed to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer. Recombinant human AOC1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Amino acid sequence: 738 aa (aa 20-751)

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans