Biovision
Human CellExp™ ABP1/AOC1, Human Recombinant
- SKU:
- 26-P1558
- UPC:
- MPN:
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- 4.0 °C
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: N/A
Synonyms: Amiloride-sensitive amine oxidase, DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, ABP, ABP1, DAO1
Alternates names: Amiloride-sensitive amine oxidase, DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, ABP, ABP1, DAO1
Taglines: Catalyzes the oxidation of biogenic amines
Taglines: USA
Country of Animal Origin: N/A
NCBI Gene ID #.: 26
NCBI Gene Symbol: AOC1
Gene Source: Human
Accession #: P19801
Recombinant: TRUE
Source: HEK 293 cells
Purity by SDS-PAGE #: >90%
Assay: SDS - PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 84.2 kDa (6 x His tag at C terminal)
Concentration: N/A
Appearance: Sterile Filtered colorless solution
Physical form description: Liquid
Reconstitution Instructions: N/A
Background Information: ABP1, also known as diamine oxidase (DAO) and amine oxidase copper domain-containing protein 1 (AOC1), is a member of the copper-containing amine oxidase family. This enzyme catalyzes the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. It has an important role in the catabolism of histamine and other bioactive polyamines. Deficiencies in ABP1 can result in histaminosis or dietary histamine intolerance. This protein is also contributed to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer. Recombinant human AOC1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Amino acid sequence: 738 aa (aa 20-751)
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
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