Human CellExp™ Activin A, Human Recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- gel pack
- Shelf Life:
- 12 months
Synonyms: Human Cellexp Human Recombinant Activin A
Alternates names: Inhba, Inhibin beta A, FSH releasing protein, FRP
Taglines: A protein complex enhancing FSH biosynthesis and secretion
Country of Animal Origin: USA
NCBI Gene ID #.: 3624
NCBI Gene Symbol: INHBA
Gene Source: Human
Accession #: P08476
Source: Human cell expressed
Purity by SDS-PAGE #: ≥95%
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 μg of protein
Activity (Specifications/test method): N/A
Biological activity: ED₅₀ is typically 0.5 to 5 ng/mL. The speciﬁc activity was determined by the dose-dependent inhibition of proliferation of the MPC-11 cell line (mouse plasmocytoma cell line).
Results: 0.5 to 5 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 25 kDa, homodimer, nonglycosylated.
Physical form description: Lyophilized from a PBS solution.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Background Information: Activins are homodimers or heterodimers of the different subunit isoforms, part of the TGF-β super-family. Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells. BioVision’s Activin A is produced in a serum-free, chemically deﬁned media.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans