Human CellExp™ Activin A, Human Recombinant

Biomolecule/Target: N/A

Synonyms: Human Cellexp Human Recombinant Activin A

Alternates names: Inhba, Inhibin beta A, FSH releasing protein, FRP

Taglines: A protein complex enhancing FSH biosynthesis and secretion

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 3624

NCBI Gene Symbol: INHBA

Gene Source: Human

Accession #: P08476

Recombinant: Yes

Source: Human cell expressed

Purity by SDS-PAGE #: ≥95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 μg of protein

Activity (Specifications/test method): N/A

Biological activity: ED₅₀ is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent inhibition of proliferation of the MPC-11 cell line (mouse plasmocytoma cell line).

Results: 0.5 to 5 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 25 kDa, homodimer, nonglycosylated.

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from a PBS solution.

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Background Information: Activins are homodimers or heterodimers of the different subunit isoforms, part of the TGF-β super-family. Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells. BioVision’s Activin A is produced in a serum-free, chemically defined media.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans