Human CellExp™ B7-H3 / CD276, Mouse recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- Gel pack
- Shelf Life:
- 12 months
Synonyms: B7-H3, CD276, B7 homolog 3
Alternates names: B7-H3, CD276, B7 homolog 3
Taglines: Regulate the T-cell-mediated immune response and a protective role in tumor cells by inhibiting natural-killer mediated cell lysis. Marker for detection of neuroblastoma cells.
Country of Animal Origin: USA
NCBI Gene ID #.: 102657
NCBI Gene Symbol: CD276
Gene Source: Mouse
Accession #: Q8VE98
Source: HEK 293 cells
Purity by SDS-PAGE #: >95%
Assay #2: N/A
Endotoxin Level: < 1 EU/μg
Activity (Specifications/test method): N/A
Biological activity: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 25.4 kDa
Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.
Background Information: B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans