Human CellExp™ B7-H5 / VISTA, Human recombinant

Biomolecule/Target: C10orf54

Synonyms: B7-H5, SISP1, Gi24, VISTA

Alternates names: VISTA protein, human VISTA protein, human recombinant VISTA protein, recombinant VISTA protein, human cell expressed VISTA protein, Human Cellexp Human Recombinant VISTA, Human recombinant VISTA, Human recombinant VISTA, Human VISTA, Human VISTA, Recombinant VISTA, Recombinant VISTA, VISTA, B7-H5, VISTA human, B7-H5 human, rhVISTA, rhB7-H5, rh Gi24, rh Gi24, rh-VISTA, rh-B7-H5, hVISTA, hB7-H5, h Gi24, March-RP-16

Taglines: Platelet receptor Gi24

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 64115

NCBI Gene Symbol: C10orf54

Gene Source: Human

Accession #: AAH20568

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: >95%

Assay: SDS-PAGE

Purity: >95%

Assay #2: N/A

Endotoxin Level: < 1 EU/μg

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein is fused with a Fc tag at C-terminus and has a calculated MW of 20 kDa.

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized

Reconstitution Instructions: Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml

Background Information: Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans