Biovision
Human CellExp™ CD71 / TFRC / TFR, human recombinant
- SKU:
- 26-7279
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: CD71 /TFRC /TFR
Synonyms: CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90
Alternates names: CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90
Taglines: A protein required for iron delivery from transferrin to cells
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 7037
NCBI Gene Symbol: TFRC
Gene Source: Human
Accession #: P02786
Recombinant: Yes
Source: HEK293 cells
Purity by SDS-PAGE #: ≥92%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: <1 EU/μg by LAL method
Activity (Specifications/test method): N/A
Biological activity: Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 μg/ml (100 μl/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml.
Results: Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 μg/ml (100 μl/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml.
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: This protein is fused with 6×His tag at the N-terminus, has a calculated MW of 76 kDa. The predicted N-terminus is Cys 89. DTT-reduced Protein migrates as 80-85 kDa due to glycosylation.
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Background Information: CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukemia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans