Human CellExp™ DPPII / QPP / DPP7, human recombinant

Biomolecule/Target: DPPII / QPP / DPP7

Synonyms: DPPII, QPP, DPP7, DPP2, Dipeptidyl peptidase 2, Dipeptidyl aminopeptidase II

Alternates names: DPPII, QPP, DPP7, DPP2, Dipeptidyl peptidase 2, Dipeptidyl aminopeptidase II

Taglines: ≥95% pure, active, human cell expressed, human recombinant DPPII / QPP / DPP7 - plays an important role in the degradation of some oligopeptides.

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 29952

NCBI Gene Symbol: DPP7

Gene Source: Human

Accession #: Q9UHL4

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGE #: ≥95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/μg by LAL method

Activity (Specifications/test method): N/A

Biological activity: Measured by its ability to cleave the fluorogenic peptide substrate, Lys-Pro-AMC (KP-AMC). The specific activity is >4000 pmol/min/µg.

Results: >4000 pmol/min/µg.

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 53 kDa. The predicted N-terminus is Gly 22. DTT-reduced Protein migrates as 60-66 kDa due to glycosylation.

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in PBS, pH 7.4. Do not vortex.

Background Information: Dipeptidyl peptidase 2 (DPP2 or DPP II) is also known as Dipeptidyl peptidase 7 (DPP7), Quiescent cell proline dipeptidase (QPP), which belongs to the peptidase S28 family. DPP7 / DPP2 is detected in seminal plasma (at protein level). When the pH is 5.5, Dipeptidyl peptidase 2 displays an optimum catalytic activity. DPP7 has low activity at pH 7 and is inactive at pH 8. DPP7 plays an important role in the degradation of some oligopeptides.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans