Human CellExp™ FGL1, Fc Tag, Human Recombinant

Biomolecule/Target: N/A

Synonyms: Fibrinogen-like protein 1, Hepassocin, HP-041, HFREP-1, LFIRE-1, HFREP1

Alternates names: Fibrinogen-like protein 1, Hepassocin, HP-041, HFREP-1, LFIRE-1, HFREP1

Taglines: a novel targets for radiation-induced lung fibrosis

Taglines: USA

Country of Animal Origin: N/A

NCBI Gene ID #.: 2267

NCBI Gene Symbol: FGL1

Gene Source: Human

Accession #: Q08830

Recombinant: True

Source: HEK 293 Cells

Purity by SDS-PAGE #: >95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Lyophilized powder

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Background Information: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: N/A