Human CellExp™ FGL1, Fc Tag, Human Recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Synonyms: Fibrinogen-like protein 1, Hepassocin, HP-041, HFREP-1, LFIRE-1, HFREP1
Alternates names: Fibrinogen-like protein 1, Hepassocin, HP-041, HFREP-1, LFIRE-1, HFREP1
Taglines: a novel targets for radiation-induced lung fibrosis
Country of Animal Origin: N/A
NCBI Gene ID #.: 2267
NCBI Gene Symbol: FGL1
Gene Source: Human
Accession #: Q08830
Source: HEK 293 Cells
Purity by SDS-PAGE #: >95%
Assay #2: N/A
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Activity (Specifications/test method): N/A
Biological activity: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Appearance: Lyophilized powder
Physical form description: Lyophilized powder
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Background Information: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.