Human CellExp™ TDGF1, Fc Tag, human recombinant

Biomolecule/Target: TDGF1

Synonyms: TDGF1, CRGF, CRIPTO

Alternates names: TDGF1, CRGF, CRIPTO

Taglines: A signaling protein involved in embryonic development and tumor growth

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 6997

NCBI Gene Symbol: TDGF1

Gene Source: Human

Accession #: P13385

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: > 92%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 42.6 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Background Information: Teratocarcinoma-derived growth factor 1 (TDGF1) is also known as Cripto-1 growth factor (CRGF), Epidermal growth factor-like cripto protein CR1, CRIPTO, is a cell membrane which contains one EGF-like domain. TDGF1 is preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. TDGF1 interacts with the activin type-1 receptor ACVR1B. TDGF1 could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans