Human CellExp™ Frizzled-5 / FZD5 Protein, Human recombinant

Biomolecule/Target: FZD5

Synonyms: FZD5, Frizzled-5, C2orf31, Fz-5, hFz5, FzE5

Alternates names: N/A

Taglines: N/A

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 7855

NCBI Gene Symbol: FZD5

Gene Source: Human

Accession #: Q13467

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: > 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 42.6 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.5. Generally Mannitol or Trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex.

Background Information: Frizzled‐5 (FZD5) is also known as FzE5, which belongs to the G‐protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta‐catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK‐3 kinase, nuclear accumulation of beta‐catenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the beta‐catenin pathway. FZD5 interacts with GOPC.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans