Human CellExp™ Frizzled-7 / FZD7 Protein, Human recombinant

Biomolecule/Target: FZD7

Synonyms: FZD7, Frizzled-7, FzE3, Fz-7, hFz7

Alternates names: FZD7, Frizzled-7, FzE3, Fz-7, hFz7

Taglines: N/A

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 8324

NCBI Gene Symbol: FZD7

Gene Source: Human

Accession #: O75084

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: > 92%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 43.3 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH 7.5. Generally Mannitol or Trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex.

Background Information: Frizzled-7 (FZD7) is also known as FzE3, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD7 contains one FZ (frizzled) domain. FZD7 is receptor for Wnt proteins. FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD7 interacts with MAGI3 and DVL1.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans