Biovision
Human CellExp™ GFRA2 / GDNFRB, Human Recombinant
- SKU:
- 26-P1736
- UPC:
- MPN:
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: N/A
Synonyms: GDNF Family Receptor Alpha-2; GDNF Receptor Beta; Neurturin Receptor Alpha; RET Ligand 2
Alternates names: GDNF Family Receptor Alpha-2; GDNF Receptor Beta; Neurturin Receptor Alpha; RET Ligand 2
Taglines: Mediates activation of RET signaling
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 2675
NCBI Gene Symbol: N/A
Gene Source: Human
Accession #: O00451
Recombinant: True
Source: HEK293 cells
Purity by SDS-PAGE #: > 95% by SDS-PAGE
Assay: N/A
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per µg as determined by the LAL method
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: ~60 to 85 kDa due to glycosylation
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized powder
Reconstitution Instructions: Reconstitute using sterile deionized water. Do not vortex.
Background Information: The GFRA2 receptor is a surface receptor attached to the cell membrane by a glycosylphosphatidylinositol linkage. GFRA2 is a receptor for glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) and mediates activation of the RET receptor tyrosine kinase. GFRA2 is a candidate target for the study of RET-associated diseases.
Amino acid sequence: Ser 22 to Ser 441 with C-terminal 6xHis Tag
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
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