Human CellExp™ Glypican 3 / GPC3, Cynomolgus Recombinant
- Usually Shipped in 5 Working Days
- 100 μg
- Storage Temperature:
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Synonyms: GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS
Alternates names: GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS
Taglines: Cell surface proteoglycan that inhibits the dipeptidyl peptidase activity of DPP4 and involved in modulation of IGF2 interactions with its receptor.
Country of Animal Origin: USA
NCBI Gene ID #.: 102137748
NCBI Gene Symbol: GPC3
Gene Source: Cynomolgus
Accession #: XP_005594665
Source: HEK293 cells
Purity by SDS-PAGE #: > 85%
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/μg
Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.
Biological activity: Immobilized Human FGF basic, Tag Free at 0.5 μg/mL (100 μl/well) can bind Cynomolgus Glypican 3, His Tag with a linear range of 1-20 ng/ml.
Binding Capacity: Immobilized Human FGF basic, Tag Free at 0.5 μg/mL (100 μl/well) can bind Cynomolgus Glypican 3, His Tag with a linear range of 1-20 ng/ml.
Unit Definition: N/A
Molecular Weight: 62.7 kDa
Physical form description: Lyophilized from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Background Information: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans