Human CellExp™ Glypican 3 / GPC3, Cynomolgus Recombinant

Biomolecule/Target: GPC3

Synonyms: GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS

Alternates names: GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS

Taglines: Cell surface proteoglycan that inhibits the dipeptidyl peptidase activity of DPP4 and involved in modulation of IGF2 interactions with its receptor.

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 102137748

NCBI Gene Symbol: GPC3

Gene Source: Cynomolgus

Accession #: XP_005594665

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGE #: > 85%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: Immobilized Human FGF basic, Tag Free at 0.5 μg/mL (100 μl/well) can bind Cynomolgus Glypican 3, His Tag with a linear range of 1-20 ng/ml.

Results: N/A

Binding Capacity: Immobilized Human FGF basic, Tag Free at 0.5 μg/mL (100 μl/well) can bind Cynomolgus Glypican 3, His Tag with a linear range of 1-20 ng/ml.

Unit Definition: N/A

Molecular Weight: 62.7 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Background Information: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans