Human CellExp™ Glypican 3 / GPC3, Human recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Synonyms: Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, GPC3, OCI5
Alternates names: GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1
Taglines: Cell surface proteoglycan that inhibits the dipeptidyl peptidase activity of DPP4 and involved in modulation of IGF2 interactions with its receptor.
Country of Animal Origin: USA
NCBI Gene ID #.: 2719
NCBI Gene Symbol: GPC3
Gene Source: Human
Accession #: P51654
Source: HEK 293 cells
Purity by SDS-PAGE #: > 90%
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.
Biological activity: Measured by its binding ability with FGF-2 in a functional ELISA. Human Glypican 3 (Cat. No. P1057) can bind Immobilized FGF-2 (Cat. No. 4037 at 0.05 μg/well) with a linear range of 2.5-600 ng/mL.
Binding Capacity: Measured by its binding ability with FGF-2 in a functional ELISA. Human Glypican 3 (Cat. No. P1057) can bind Immobilized FGF-2 (Cat. No. 4037 at 0.05 μg/well) with a linear range of 2.5-600 ng/mL.
Unit Definition: N/A
Molecular Weight: 61.7 kDa
Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with 5% Trehalose added as protectant before lyophilization.
Reconstitution Instructions: Reconstitute in sterile PBS, pH 7.
Background Information: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans