Human CellExp™ Glypican 3 / GPC3, Fc Tag, Human Recombinant

Biomolecule/Target: GPC3

Synonyms: GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1

Alternates names: GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1

Taglines: Cell surface proteoglycan that inhibits the dipeptidyl peptidase activity of DPP4 and involved in modulation of IGF2 interactions with its receptor.

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 2719

NCBI Gene Symbol: GPC3

Gene Source: Human

Accession #: P51654

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: >90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/μg

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: Immobilized Human FGF basic, Tag Free at 2μg/mL (100 μL/well) can bind Human Glypican 3, Fc Tag with a linear range of 0.48-7.8 ng/mL

Results: N/A

Binding Capacity: Immobilized Human FGF basic, Tag Free at 2μg/mL (100 μL/well) can bind Human Glypican 3, Fc Tag with a linear range of 0.48-7.8 ng/mL

Unit Definition: N/A

Molecular Weight: 87.4 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally Trehalose is added as protectant before lyophilization.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.

Background Information: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans