Human CellExp™ IFN-alpha 2a, Human Recombinant

Biomolecule/Target: N/A

Synonyms: Human Cellexp Human Recombinant IFN-alpha 2a

Alternates names: Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN-α 2a.

Taglines: A critical cytokine for innate and adaptive immunity

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 3440

NCBI Gene Symbol: IFNA2

Gene Source: Human

Accession #: P01563

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGE #: ≥95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 μg of protein

Activity (Specifications/test method): N/A

Biological activity: ED₅is typically 0.1 to 0.4 ng/mL. The specific activity was determined by the dose-dependent cytotoxicity of the human TF -1 cell line(human erythroleukemic indicator cell line).

Results: 0.1 to 0.4 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 16 kDa, monomer, glycosylated

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from a TBS solution.

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Background Information: Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens. They belong to the large class of glycoproteins known as cytokines. IFN-alpha is produced by macrophages and has antiviral activities. IFNs also have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans