Human CellExp™ IL-28B, Human Recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- gel pack
- Shelf Life:
- 12 months
Synonyms: Human Cellexp Human Recombinant IL-28B
Alternates names: Interleukin-28A, IL-28A, IFN-Lambda 2, Interferon-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20.
Taglines: A cytokine mediating adaptive immune response
Country of Animal Origin: China
NCBI Gene ID #.: 282617
NCBI Gene Symbol: IFNL3
Gene Source: Human
Accession #: Q8IZI9
Source: Human 293 cell expressed
Purity by SDS-PAGE #: > 95%
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 μg of protein
Activity (Specifications/test method): N/A
Biological activity: ED₅₀ is typically 0.1 to 1 ng/mL. The specific activity was determined by the dose-dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus.
Results: 0.1 to 1 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 24 kDa, monomer, non-glycosylated
Physical form description: Lyophilized in PBS.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Background Information: IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans