Biovision
Human CellExp™ IL-4, Human Recombinant
- SKU:
- 26-6463
- UPC:
- MPN:
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20°C
- Shipping Conditions:
- gel pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: N/A
Synonyms: Human Cellexp Human Recombinant IL-4
Alternates names: BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra.
Taglines: A key regulator in humoral and adaptive immunity
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 3565
NCBI Gene Symbol: IL4
Gene Source: Human
Accession #: P05112
Recombinant: Yes
Source: Human 293 cell expressed
Purity by SDS-PAGE #: ≥95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 μg of protein
Activity (Specifications/test method): N/A
Biological activity: ED₅₀ is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent simulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
Results: 0.1 to 0.5 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 14 and 19 kDa, monomer
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from a solution of 20 mM Tris-HCl, pH 7.4, with 300 mM NaCl.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Background Information: IL4 is a pleiotropic cytokine and a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
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