Human CellExp™ IL20RB /IL-20R2, human recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Biomolecule/Target: IL20RB /IL-20R2
Synonyms: IL20RB, IL-20R2, IL-20R-beta, DIRS1, FNDC6
Alternates names: IL20RB, IL-20R2, IL-20R-beta, DIRS1, FNDC6
Taglines: A receptor for IL19, IL20 and IL24
Country of Animal Origin: USA
NCBI Gene ID #.: 53833
NCBI Gene Symbol: IL20RB
Gene Source: Human
Accession #: Q6UXL0
Source: HEK293 cells
Purity by SDS-PAGE #: ≥90%
Assay #2: N/A
Endotoxin Level: <1 EU/μg by LAL method
Activity (Specifications/test method): N/A
Biological activity: Measured by its binding ability in a functional ELISA. When Recombinant Human IL‑19 protein is present at 0.2 µg/mL, the concentration of rhIL20RB Fc Chimera that produces 50% of the optimal binding response is approximately 5‑50 ng/ml.
Results: Measured by its binding ability in a functional ELISA. When Recombinant Human IL‑19 protein is present at 0.2 µg/mL, the concentration of rhIL20RB Fc Chimera that produces 50% of the optimal binding response is approximately 5‑50 ng/ml.
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: This protein fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 49.1 kDa. The predicted N-terminus is Asp 30. As a result of glycosylation, DTT-reduced Protein migrates as 50 kDa and non-reduced protein migrates as 100 kDa.
Physical form description: Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH 7.0. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Background Information: Interleukin-20 receptor subunit beta (IL20RB) is also known as IL-20R2, DIRS1, which belongs to the type II cytokine receptor family. IL20RB / IL-20R2 contains two fibronectin type-III domains. IL20RB / IL-20R2 is widely expressed with highest levels in skin and testis. IL20RB can be fused with IL20RA or IL22RA1 forming heterodimer. The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans