Human CellExp™ LAG-3 / CD223, Cynomolgus Recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Synonyms: LAG3, CD223, FDC
Alternates names: LAG3, CD223, FDC
Taglines: A protein involved in lymphocyte activation
Country of Animal Origin: USA
NCBI Gene ID #.: 102122272
NCBI Gene Symbol: LAG-3
Gene Source: Cynomolgus
Accession #: XP_005570011.1
Source: HEK293 cells
Purity by SDS-PAGE #: > 85%
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/μg
Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.
Biological activity: Immobilized Cynomolgus LAG-3, mouse IgG2a Fc tag at 2 μg/mL (100 μl/well) can bind Anti-LAG3 MAb,Human IgG1 with a linear range of 3-20 ng/ml.
Binding Capacity: Immobilized Cynomolgus LAG-3, mouse IgG2a Fc tag at 2 μg/mL (100 μl/well) can bind Anti-LAG3 MAb,Human IgG1 with a linear range of 3-20 ng/ml.
Unit Definition: N/A
Molecular Weight: 73.7 kDa
Physical form description: Lyophilized from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Background Information: Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans