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- Human CellExp™ LAG3 / CD223, Fc Tag, human recombinant
Biovision
Human CellExp™ LAG3 / CD223, Fc Tag, human recombinant
- SKU:
- 26-P1149
- UPC:
- MPN:
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: LAG3
Synonyms: LAG3, CD223, FDC
Alternates names: LAG3, CD223, FDC
Taglines: A protein involved in lymphocyte activation
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 3902
NCBI Gene Symbol: LAG3
Gene Source: Human
Accession #: P18627
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGE #: > 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/μg
Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.
Biological activity: Immobilized Human LAG-3, Fc Tag at 2μg/mL (100 μL/well) can bind Anti-LAG3 MAb, Human IgG1 with a linear range of 0.1-2 ng/mL.
Results: N/A
Binding Capacity: Immobilized Human LAG-3, Fc Tag at 2μg/mL (100 μL/well) can bind Anti-LAG3 MAb, Human IgG1 with a linear range of 0.1-2 ng/mL.
Unit Definition: N/A
Molecular Weight: 72.3 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Background Information: Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
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