Human CellExp™ LAMP1/CD107a, human recombinant

Biomolecule/Target: LAMP1/CD107a

Synonyms: LAMP1, CD107a

Alternates names: LAMP1, CD107a

Taglines: A glycoprotein which provides selectins with carbohydrate ligands

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 3916

NCBI Gene Symbol: LAMP1

Gene Source: Human

Accession #: P11279

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGE #: ≥95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/μg by LAL method

Activity (Specifications/test method): N/A

Biological activity: Measured by its binding ability in a functional ELISA. When rhLAMP1 /CD107a is coated at 1 µg/ml, rhGalectin‑3 (Cat # 4684) binds with an apparent Kd <30 nM.

Results: Measured by its binding ability in a functional ELISA. When rhLAMP1 /CD107a is coated at 1 µg/ml, rhGalectin‑3 (Cat # 4684) binds with an apparent Kd <30 nM.

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 39.2 kDa. The predicted N-terminus is Ala 29. DTT-reduced Protein migrates as 60-100 kDa due to different glycosylation.

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Background Information: Lysosomal-associated membrane protein 1 (LAMP1) is also known as CD107a (Cluster of Differentiation 107a). LAMP1 / CD107a belongs to the LAMP family. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans