Human CellExp™ LILRB2, human recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Synonyms: LILRB2, ILT4, LIR2, MIR10, CD85d
Alternates names: LILRB2, ILT4, LIR2, MIR10, CD85d
Taglines: Receptor for class I MHC antigens
Country of Animal Origin: USA
NCBI Gene ID #.: 10288
NCBI Gene Symbol: LILRB2
Gene Source: Human
Accession #: Q8N423
Source: HEK 293 cells
Purity by SDS-PAGE #: > 85%
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/μg
Activity (Specifications/test method): N/A
Biological activity: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 74.4 kDa
Physical form description: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Background Information: Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans