Human CellExp™ NKp46 / NCR1 / CD335, Human Recombinant
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Synonyms: NCR1, LY94, CD335, NK-p46, hNKp46
Alternates names: NCR1, LY94, CD335, NK-p46, hNKp46
Taglines: Cytotoxicity-activating receptor contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis
Country of Animal Origin: USA
NCBI Gene ID #.: 9437
NCBI Gene Symbol: NCR1
Gene Source: Human
Accession #: O76036
Source: HEK 293 cells
Purity by SDS-PAGE #: >90%
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.3 kDa. The protein migrates as 36-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Appearance: Lyophilized powder
Physical form description: Lyophilized
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Background Information: Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Amino acid sequence: Gln 22 - Asn 254
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans