Human CellExp™ NKp46 / NCR1 / CD335, Human Recombinant

Biomolecule/Target: N/A

Synonyms: NCR1, LY94, CD335, NK-p46, hNKp46

Alternates names: NCR1, LY94, CD335, NK-p46, hNKp46

Taglines: Cytotoxicity-activating receptor contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 9437

NCBI Gene Symbol: NCR1

Gene Source: Human

Accession #: O76036

Recombinant: True

Source: HEK 293 cells

Purity by SDS-PAGE #: >90%

Assay: N/A

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.3 kDa. The protein migrates as 36-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Lyophilized

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Background Information: Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Amino acid sequence: Gln 22 - Asn 254

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans