Human CellExp™ SARS-CoV-2 Spike RBD (E484K)
- Usually Shipped in 5 Working Days
- 50 μg
- Storage Temperature:
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Synonyms: COVID-19 Spike RBD protein (E484K); 2019-nCoV Spike RBD protein (E484K); SARS-CoV-2 Mutant (E484K); SARS-CoV-2 (E484K) mutant protein
Alternates names: COVID-19 Spike RBD protein (E484K); 2019-nCoV Spike RBD protein (E484K); SARS-CoV-2 Mutant (E484K); SARS-CoV-2 (E484K) mutant protein
Taglines: Spike RBD variant with E84k mutation which mildly increase receptor binding
Country of Animal Origin: USA
NCBI Gene ID #.: N/A
NCBI Gene Symbol: N/A
Gene Source: Coronavirus
Accession #: YP_009724390.1
Purity by SDS-PAGE #: ≥ 90% by SDS-PAGE
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 35 kDa
Appearance: Lyophilized protein
Physical form description: N/A
Reconstitution Instructions: Reconstitute in sterile water to a concentration of 1 mg/ml.
Background Information: SARS-CoV-2 Spike protein is a large type I transmembrane protein composed of S1 subunit and S2 subunit. During viral infection, the receptor-binding domain (RBD) of the S1 subunit is responsible for the recognition and binding of host receptor ACE2, while the S2 subunit mediates viral cell membrane fusion. The SARS-CoV-2-S1-RBD/ACE2 interaction mediates viral entry into the target cells. The E484K mutant mildly increase receptor binding.
Amino acid sequence: The target protein SARS-CoV-2 S Protein RBD (E484K) is expressed with His tag at the C-terminus.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans