Biovision
Human CellExp™ SARS-CoV-2 Spike RBD (L452R, T478K), Recombinant
- SKU:
- 26-P1744
- Availability:
- Usually Shipped in 5 Working Days
- Size:
- 100 µg
- Storage Temperature:
- -20°C
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: N/A
Synonyms: COVID-19 Spike RBD protein; 2019-nCoV Spike RBD protein; SARS-CoV-2 Mutant (L452R, T478K)
Alternates names: N/A
Taglines: Recombinant Spike RBD mutant of the SARS-CoV-2 Delta variant
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: 43740568
NCBI Gene Symbol: N/A
Gene Source: SARS-CoV-2
Accession #: P0DTC2
Recombinant: True
Source: HEK 293 cells
Purity by SDS-PAGE #: ≥ 90% by SDS-PAGE
Assay: N/A
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1 EU per 1 µg of protein as determined by LAL method
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 26.6 kDa (calculated); 33-35 kDa (observed due to glycosylation)
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized powder
Reconstitution Instructions: N/A
Background Information: SARS-CoV-2 Spike protein is a large type I transmembrane protein composed of S1 subunit and S2 subunit. During viral infection, the receptor-binding domain (RBD) of the S1 subunit is responsible for the recognition and binding of host receptor ACE2, while the S2 subunit mediates viral cell membrane fusion. The SARS-CoV-2-S1-RBD/ACE2 interaction mediates viral entry into the target cells. The mutations at L452R and T478K were identified in the SARS-CoV-2 Delta (particularly B.1.617.2) variants that originated in India.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans