Biovision
Human CellExp™ Soluble NRP-1, Human Recombinant
- SKU:
- 26-P1662
- UPC:
- MPN:
- Availability:
- Usually Shipped in 5 Working Days
- Storage Temperature:
- -20ºC
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Description
Biomolecule/Target: N/A
Synonyms: Natural soluble neuropilin-1, soluble neuropilin-1, SNRP1, Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD304,NRP, VEGF165R, UniProt O14786-2, isoform 2 Human CellExp™ Soluble neuropilin-1, Human Recombinant
Alternates names: N/A
Taglines: A membrane-bound receptor for both vascular endothelial growth factor and semaphorin family members.
Taglines: USA
Country of Animal Origin: USA
NCBI Gene ID #.: N/A
NCBI Gene Symbol: N/A
Gene Source: Human
Accession #: UniProt O14786-2
Recombinant: True
Source: HEK 293 cells (Phe 22 - Lys 644)
Purity by SDS-PAGE #: ≥ 95% by SDS-PAGE gel
Assay: N/A
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: Expected weight of 71 kDa (6x His tag at the C-terminus)
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.
Background Information: Neuropilin-1 isoform 2 (identifier: O14786-2) is also known as soluble NRP1 or SNRP1. The sequence of this isoform differs from the canonical sequence by 3 amino acids (aa 642-644, EFP → GIK). NRP1 is a membrane-bound receptor for both vascular endothelial growth factor and semaphorin family members. NRP1 has been implicated in vascularization and progression of cancers. A positive correlation has been shown between elevated NRP1 expression and tumor samples of the brain, prostate, breast, colon and lung. Soluble NRP1 is expressed differently than the intact NRP1 and is also a VEGF165 antagonist. Recently studies have shown that NRP1 binds to the S1 domain of SARS-CoV-2 spike protein via its b1 domain (aa 273-427). This may facilitate the entry of SARS-CoV-2 virus into the cells thereby making it a potential target for future antiviral drugs.
Amino acid sequence: Phe 22 - Lys 644
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
Related Products

Human CellExp™ GAD1, human recombinant
Biovision

Human CellExp™ PD-1 /PDCD1, human recombinant
Biovision

Human CellExp™ IGF-1, human recombinant
Biovision

Human CellExp™ NOV, human recombinant
Biovision

Human CellExp™ Dermatopontin, Human Recombinant
Biovision
Customers Also Viewed

Growth Factor Set II, StemBoost™
Biovision

EZCell™ Glutathione Detection Kit (Blue Fluorescence)
Biovision

Human CellExp™ Contactin-6 (Fc Tag), Human Recombinant
Biovision

Human CellExp™ Contactin-5 (His Tag), Human Recombinant
Biovision

Human CellExp™ Ephrin-A1 / EFNA1 (Active), Human Recombinant
Biovision

Human CellExp™ IL-1α, Human Recombinant
Biovision

Human CellExp™ Biotinylated CD80/B7-1, Human Recombinant
Biovision

Human CellExp™ SARS-CoV-2 S1, Recombinant
Biovision

Human CellExp™ SARS-CoV-2 S1 (E484K), Recombinant
Biovision

Human CellExp™ CD3 epsilon (His-tag) & CD3 delta Heterodimer
Biovision

Human CellExp™ SARS-CoV-2 Spike RBD (E484K)
Biovision

Human CellExp™ SARS-CoV-2 Spike RBD (K417N, E484K, N501Y)
Biovision

Human CellExp™ LYPD3
Biovision

Human CellExp™ CD8b, Human Recombinant
Biovision

Human CellExp™ LILRB4 / CD85k / ILT3, Cynomolgus Recombinant
Biovision

Human CellExp™ LAG-3 / CD223, Cynomolgus Recombinant
Biovision

Human CellExp™ DLL4, Mouse Recombinant
Biovision

EZBlock™ Blocking Buffer and Signal Enhancer
Biovision

StemBoost™ Growth Factor Set IX
Biovision

StemBoost™ Growth Factor Set VI
Biovision

StemBoost™ Growth Factor Set V
Biovision

Growth Factor Set IV, StemBoost™
Biovision

DiaEasy™ Dialyzer (3 ml) MWCO 3.5 kDa
Biovision

ToxOut™ Endotoxin Rapid Removal Agarose
Biovision

ToxOut™ Endotoxin Removal Equilibration Buffer
Biovision

EZSolution™ Protein Stabilizer
Biovision

Human CellExp™ IL-22, human recombinant
Biovision

Human CellExp™ Furin, human recombinant
Biovision

EZDetect™ Polyubiquitin Probe (Biotin conjugated)
Biovision

Human CellExp™ SCF, Human Recombinant
Biovision

Human CellExp™ Progranulin, Mouse Recombinant
Biovision

EZBlock™ T20 (PBS) Blocking Buffer
Biovision

EZBlock™ T20 (TBS) Blocking Buffer
Biovision

EZBlock™ (PBS) Blocking Buffer
Biovision

EZBlock™ (TBS) Blocking Buffer
Biovision

ECOSURF™ EH-9, MegaPure™ Detergent, 10% Solution
Biovision

DiscoveryPak™ Antiviral Agents Set
Biovision

StemBoost™ Reprogramming Cocktail, VCRFBI, Sterile-Filtered (100X)
Biovision

DiscoveryPak™ FLT3 Kinase Inhibitor Set
Biovision

DiscoveryPak™ SGLT-2 Inhibitors Set
Biovision

EZBlock™ Protease Inhibitor Cocktail XVI
Biovision

EZSolution™ Penicillin/Streptomycin/Amphotericin B, Sterile-Filtered (100X)
Biovision

OxiRed™ Probe
Biovision

recMAb™ Anti-KIM-1 Antibody
Biovision

recMAb™ Anti-S100A9 Antibody
Biovision

recMAb™ Anti-LOXL2 Antibody
Biovision

recMAb™ Anti-Osteopontin Antibody
Biovision

recMAb™ Anti-p53 Antibody
Biovision

Anti-NKX2.2 recMAb™ Antibody
Biovision

Anti-MYOD1 recMAb™ Antibody
Biovision