OryzaExp™ Epidermal Growth Factor, Human Recombinant

Biomolecule/Target: N/A

Synonyms: Recombinant epidermal growth factor, Plant-derived EGF, recombinant EGF, rEGF, EGF

Alternates names: Recombinant epidermal growth factor, Plant-derived EGF, recombinant EGF, rEGF, EGF

Taglines: A growth factor stimulating DNA synthesis, cell growth and proliferation by binding to EGFR

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 1950

NCBI Gene Symbol: N/A

Gene Source: Human

Accession #: AAS83395

Recombinant: False

Source: Oryza Sativa (Rice)

Purity by SDS-PAGE #: > 95%

Assay: N/A

Purity: N/A

Assay #2: N/A

Endotoxin Level: ≤5EU/mg

Activity (Specifications/test method): The bioactivity determined by a cell proliferation assay using Balb/c 3T3, corresponding to a specific activity of ≥ 1×106 Units/mg.

Biological activity: The bioactivity determined by a cell proliferation assay using Balb/c 3T3, corresponding to a specific activity of ≥ 1×106 Units/mg.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 5.3KDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: White lyophilized powder

Reconstitution Instructions: It is recommended to reconstitute OryzaExp™EGF at 100-200ug/ml in sterile water. Further dilutions can be made in other aqueous buffer.

Background Information: Human epidermal growth factor, also known as EGF, is a 6kD protein with 53 amino acid residues and three intramolecular disulfide bonds. By binding with high affinity to epidermal growth fact receptor (EGFR) on the cell surface, EGF results in a variety of biochemical changes within the cell, rising intracellular calcium levels, increasing glycolysis, protein synthesis and regulating the gene expression, including the gene for EGFR that ultimately lead to DNA synthesis and cell proliferation.

Amino acid sequence: NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR

Handling: Centrifuge the vial prior to opening.

Usage: N/A