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Human CellExp™ TIM3/HAVR2 Protein, Human Recombinant

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SKU:
26-P1002
Availability:
Usually Shipped in 5 Working Days
Storage Temperature:
4°C in lyophilized state
Shipping Conditions:
Gel pack
Shelf Life:
12 months
€333.00 - €1,227.00
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Description

Biomolecule/Target: TIM3/HAVR2

Synonyms: Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3

Alternates names: Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3

Taglines: TIM3 inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

Taglines: USA

Country of Animal Origin: USA

NCBI Gene ID #.: 84868

NCBI Gene Symbol: HAVCR2

Gene Source: Human

Accession #: Q8TDQ0

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGE #: ≥95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <0.01 EU/μg

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 20.7 kDa. The predicted N-terminus is Ser 22. DTT-reduced Protein migrates as 28-48 kDa due to glycosylation.

Concentration: N/A

Appearance: Dry powder

Physical form description: Lyophilized powder

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH7.4) to a stock solution of 400 µg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage.

Background Information: Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.

Amino acid sequence: Ser 22 - Arg 220

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans

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