Human CellExp™ Siglec-6 / CD327 Protein, Fc Tag
- Usually Shipped in 5 Working Days
- Storage Temperature:
- Shipping Conditions:
- Gel Pack
- Shelf Life:
- 12 months
Biomolecule/Target: Siglec-6 / CD327 Fc Tag
Synonyms: SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327
Alternates names: SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327
Taglines: A cell surface protein primarily on the surface of immune cells that mediates sialic-acid dependent binding to cells.
Country of Animal Origin: USA
NCBI Gene ID #.: 946
NCBI Gene Symbol: SIGLEC6
Gene Source: Human
Accession #: O43699
Source: HEK293 cells
Purity by SDS-PAGE #: >92%
Assay #2: N/A
Endotoxin Level: <1 EU/μg by LAL method
Activity (Specifications/test method): N/A
Biological activity: Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn).
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 60.3 kDa
Appearance: Dry powder
Physical form description: Lyophilized powder
Reconstitution Instructions: . Reconstitute in sterile deionized water to a stock solution of 200 µg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage.
Background Information: Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Amino acid sequence: Gln 16 - Val 320
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans