Biovision Biochemicals

A 10 mM (5 mg in 1740 µl) of the ALK5 inhibitor RepSox (Cat. No. 1894) in anhydrous DMSO.Alternate Name/Synonyms: 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E-616452Appearance:...

A 10 mM (1 mg in 231 µl) of the ROCK inhibitor GSK429286A (Cat. No. 2637) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 206 µl) of the GSK-3 inhibitor CHIR-98014 (Cat. No. 2595) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1744 µl) of the PDK1 activator PS48 (Cat. No. 1869) in anhydrous DMSO.Alternate Name/Synonyms: (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic acidAppearance: LiquidAppearance: A 10 mM...

A sterile-filtered solution (50 mg/ml) of the antibiotic Hygromycin B (Cat. No. 2589) in PBS buffer.Alternate Name/Synonyms:...

A small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits...

Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1, <4 nM for mSCD1). Also exhibited in vivo efficacy with dose-dependent...

Cell-permeable. A potent, selective , reversible and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM in the presence of 5 µM ATP and no AMP). Does not affect the...

A potent, cell-permeable JAK2 inhibitor. A novel analog of the JAK2 inhibitor AG490 (Cat. No. 1570-5) that blocks STAT3 and phosphoinositide-3-kinase pathways. It is significantly more potent and...

Cyclopamine blocks activation of the Hedgehog response pathway associated with mutations that either activate the proto-oncogene Smoothened (Smo) or inactivate the tumour suppressor Patched (Ptch)...

A cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 0.5 nM). Inhibits neutral cysteine proteases and the proteasome (Ki =...

Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the...

Potent, broad spectrum matrix metalloprotease (MMP) inhibitor (IC₅₀ values are 3, 4, 4, 6 and 20 nM for MMP -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and...

A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes...

Cell-permeable, small molecule agonist of TGR5 G-protein coupled receptor. This agonist has shown to increase glucagon like peptide-1 (GLP-1) secretion from primary intestinal cells.Alternate...

Inhibitor of TNF-α processing (IC₅₀ = 100 nM), similar to TAPI-0 (Cat. No. 2067-1), but more stable in tissue culture and in vivo. Inhibits TACE and other metalloproteases. Blocks release of TNF- α...

A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (Cat. No. 1864) (EC₅₀ = 210 nM versus EC₅₀ = 490 nM), as well as showing no nonspecific...

Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor (IC₅₀ = 37 nM). It raises high-density lipoprotein (HDL) cholesterol and reduces low-density lipoprotein (LDL) cholesterol levels...

Dalcetrapib is a potent CETP modulator. It is a thioester pro-drug that is rapidly hydrolyzed to generate a pharmacologically active thiol. Dalcetrapib modulates cholesteryl ester transfer protein...

Anacetrapib is a potent inhibitor of the cholesteryl ester transfer protein (CETP)-dependent transfer of cholesteryl ester (CE) (IC₅₀ = 17 ± 4.8 nM); it significantly raises HDL cholesterol levels in...

Supplied as a 100X concentrated sterile-filtered solution. Pencillin/Streptomycin/Amphotericin B contains 10,000 IU/ml of Penicillin potassium (Cat. No. 2504), 10 mg/ml of Streptomycin sulfate (Cat...

Supplied as a 100X concentrated sterile-filtered solution. Pencillin-Streptomycin (Pen/Strep) is an antibacterial solution comprised of Penicillin (10,000 units/ml), a β-lactam, and Streptomycin (10...

A solution (34 mg/ml, 0.2 µM sterile filtered) of Chloramphenicol (Cat. No. 2486) in 100% Ethanol. Suitable for cell culture applications.Alternate Name/Synonyms:...

Ampicillin sodium is a β-lactam antibiotic structurally related to penicillin. Inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell...

A 10 mM (5 mg in 874 µl) solution of the of the EZH2 inhibitor EPZ6438 (Cat. No.2383) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 178 µl) solution of the of DOT1L methyltransferase inhibitor EPZ5676 (Cat. No. 2382) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 381 µl) solution of the EZH2 inhibitor 3-Deazaneplanocin (Cat. No. 2060) in anhydrous DMSO.Alternate Name/Synonyms: DZNep; NSC 617989;...

A 10 mM (2 mg in 370 µl) solution of the EZH2 inhibitor EPZ-005687 (Cat. No. 2364) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 190 µl) solution of the EZH2 inhibitor GSK126 (Cat. No. 2282) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (1 mg in 185 µl) solution of the EZH2 inhibitor GSK343 (Cat. No. 2281) in anhydrous DMSO.Alternate Name/Synonyms:...

A 100 mM (25 mg in 1007 µl) sterile-filtered solution of Tetrahydrouridine (Cat. No.1671) in H₂O.Alternate Name/Synonyms: 2(1H)-pyrimidinone, tetrahydro-4-hydroxy-1-beta-D-ribofuranosyl-, NSC112907;...

A potent, selective and ATP-competitive mTOR inhibitor (IC₅₀ = 2.1 nM for mTORC1). Torin 2 displays 800-fold selectivity for mTOR over PI3K (cellular EC₅₀ values of 0.25 nM and 200 nM, respectively)...

A potent, selective and ATP-competitive mTOR inhibitor, with IC₅₀ values of 2 and 10 nM for mTORC1 and mTORC2 respectively; Torin1 displays 1000-fold selectivity for mTOR over PI3K (EC₅₀ = 1800 nM)...

A cell- permeable activator of AMP-activated protein kinase (AMPK), a metabolic sensor involved in both cellular and whole body energy homeostasis. In vivo, pharmacologic activation of AMPK with...

Antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption...

A 10 mM (1 mg in 330 µl) of Trichostatin A (Cat. No. 1606-1) in anhydrous DMSO.Alternate Name/Synonyms: TSA,...

A 10 mM (1 mg in 260 µl) solution of the proteasome inhibitor PS-341 (Cat. No. 1846) in anhydrous DMSO.Alternate Name/Synonyms: MG-341;...

A 10 mM (1 mg in 217 µl) solution of the proteasome inhibitor MG-115 (Cat. No. 1831) in anhydrous DMSO.Alternate Name/Synonyms: Z-LL-NVa-CHO; Z-Leu-Leu-Nva-CHO; MG115Appearance: LiquidAppearance:...

A non-ionic detergent with a low cloud point (23 °C) assisting in protein solubilization with phase-partitioning of hydrophilic from amphiphilic proteins.Alternate Name/Synonyms:...

A non-ionic surfactant, used to solubilize cerebral GABA receptors and for solubilization of proteins and lipids of the scallop gill ciliary membrane and of membranes from breast cancer tumors...

A non-ionic detergent useful for the extraction of membrane-bound proteins as well as isolation of nuclei from mammalian cell lines.Alternate Name/Synonyms: POE (20) sorbitan monooleate, Polyethylene...

A non-ionic detergent useful for the isolation of membrane-bound proteins under non-denaturing conditions.Alternate Name/Synonyms: Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan...

A non-ionic detergent useful for the isolation of membrane-bound proteins under non-denaturing conditions. Also useful for 2D-electrophoresis applications.Alternate Name/Synonyms:...

A 10 mM (1 mg in 219 µl) solution of the Bromodomain inhibitor (+)-JQ1 (Cat. No. 2070-1) in anhydrous DMSO.Alternate Name/Synonyms:...

A 5% solution of the non-ionic detergent Digitonin (Cat.# 2081) in deionized water.Alternate Name/Synonyms: DigitinAppearance: LiquidAppearance: A 5% solution in H₂OAppearance: 11024-24-1Appearance:...

A 100 mM (25 mg in 392 μl) solution of BAY 43-9006 (Cat. No.1594-25) in anhydrous DMSO.Alternate Name/Synonyms: Nexavar, SorafenibAppearance: LiquidAppearance: A 100 mM solution in DMSOAppearance:...

A 10 mM (5 mg in 1.12 ml) solution of Gefitinib (Cat. No. 1589-5) in anhydrous DMSO.Alternate Name/Synonyms: ZD-1839Appearance: LiquidAppearance: A 10 mM solution in DMSOAppearance:...

A 100 mM (25 mg in 512 µl) solution of Dasatinib (Cat. No. 1586-25) in anhydrous DMSO.Alternate Name/Synonyms: BMS-354825; SprycelAppearance: LiquidAppearance: A 100 mM solution in DMSOAppearance:...

A 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 1645) in anhydrous DMSO.Alternate Name/Synonyms: 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-meth yl-1H-pyrrole-3-propanoic acidAppearance:...

A 10 mM (3.20 mg in 1 ml) solution of the ROCK inhibitor Y-27632, Dihydrochloride (Cat. No. 1596) in deionized water.Alternate Name/Synonyms: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecar...

A 5 mM (1.56 mg in 1 ml), sterile-filtered solution of the enhancer of hESCs survival Thiazovivin (Cat. No. 1681) in anhydrous DMSO.Alternate Name/Synonyms:...

A 5 mM (1.92 mg in 1 ml), sterile-filtered solution of the ALK5 inhibitor SB-431542 (Cat. No. 1674) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (4.65 mg in 1 ml), sterile-filtered solution of the GSK-3β inhibitor CHIR99021 (Cat. No. 1677) in anhydrous DMSO.Alternate Name/Synonyms:...

A 5 mM (2.41 mg in 1 ml), sterile-filtered solution of the MEK inhibitor PD-0325901 (Cat. No. 1643) in anhydrous DMSO.Alternate Name/Synonyms:...

A 5 mM (2.1 mg in 1 ml), sterile-filtered solution of the ALK5 inhibitor A83-01(Cat. No. 1725) in anhydrous DMSO.Alternate Name/Synonyms: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-p...

A 10 mM (1 mg in 260 µl) solution of SB-431542 (Cat. No. 1674-1) in anhydrous DMSO.Alternate Name/Synonyms: 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamideAppearance:...

A 10 mM (1 mg in 209 µl) solution of PD184352 (Cat. No. 1585-1) in anhydrous DMSO.Alternate Name/Synonyms: CI-1040Appearance: LiquidAppearance: 10 mM (DMSO)Appearance: 212631-79-3Appearance:...

A solution (10 mg/ml, 0.2 µM sterile filtered) of Puromycin Dihydrochloride (Cat. No.1860-100) in deionized water. Suitable for cell culture applications.Alternate Name/Synonyms:...

A 100 mM (25 mg in 469.4 µl) solution of Sunitinib Malate (Cat. No. 1611-25) in anhydrous DMSO.Alternate Name/Synonyms: Sunitinib Maleate, SU-11248, Sutent, PHA-290940AD, PNU-290940ADAppearance:...

A 100 mM (25 mg in 538.1 µl) solution of Tozasertib (Cat. No. 1595-25) in anhydrous DMSO.Alternate Name/Synonyms: MK-0457, VX6, VX-681Appearance: LiquidAppearance: 100 mM (DMSO)Appearance:...

An excellent buffer in the pH range of 6.2-7.8. Imidazole has a pKa of 7.0 at 20°C.Alternate Name/Synonyms: 1,3-Diazacyclopenta-2,4-diene; 1,3-diazoleAppearance: White solidAppearance: N/AAppearance:...

A 10 mM (5 mg in 1051 µl) solution of MG-132 (Cat. No.1703-5) in anhydrous DMSO.Alternate Name/Synonyms: Z-Leu-Leu-Leu-CHO; Z-LLL-CHOAppearance: LiquidAppearance: N/AAppearance:...

A 10 mM (1 mg in 265 µl) solution of SB 203580 (Cat. No. 1712-1) in anhydrous DMSO.Alternate Name/Synonyms: [4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazoleAppearance:...

A 10 mM (500 µg in 132 µl) solution of Gö 6976 (Cat. No. 1711-500) in anhydrous DMSO.Alternate Name/Synonyms: 5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]py-...

A 10 mM (5 mg in 1550 µl) solution of Y-27632, Dihydrochloride (Cat. No. 1596-5) in deionized water.Alternate Name/Synonyms: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecar boxamide...

A 10 mM (5 mg in 1870 µl) solution of PD98059 (Cat. No. 1666-5) in anhydrous DMSO.Alternate Name/Synonyms: 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-oneAppearance: LiquidAppearance: 10 mM...

A 10 mM (5 mg in 1075 µl) solution of CHIR99021 (Cat. No. 1677-5) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg/1627 µl) solution of PI -3 Kinase inhibitor LY 294002 (Cat. No.1667-5) in DMSO.Alternate Name/Synonyms: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneAppearance: LiquidAppearance: 10...

A 5 mM (5 mg in 1093 µl) solution of Rapamycin (Cat. No. 1568-5) in DMSO.Alternate Name/Synonyms: 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, AY 22989, SirolimusAppearance:...

A 1 mM (100 µg/214 µl) solution of Staurosporine (Cat. No. 1048-01) in DMSO.Alternate Name/Synonyms: Antibiotic AM-2282Appearance: LiquidAppearance: 1 mM (DMSO)Appearance: 62996-74-1Appearance:...

A 10 mM ( 1 mg in 221 µl) of Pyrintegrin (Cat. No. 1729-1) in anhydrous DMSO.Alternate Name/Synonyms:...

Cell-permeable. A 10 mM (1 mg in 321 µl) solution of Thiazovivin (Cat. No. 1681-1) in anhydrous DMSO.Alternate Name/Synonyms: N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamideAppearance:...

Cell-permeable. A potent and selective γ-secretase inhibitor (IC₅₀ = 17 nM) .Displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for...

OxiRed, which has been marketed under the name Amplex Red™ reagent, is a highly sensitive and stable probe for H₂O₂, is a fluorogenic (EX/EM = 535/587 nm) and Colorometric (l = 570 nm) substrate for...

ABTS is considered a safe and sensitive substrate compatible for horseradish peroxidase (HRP) based ELISA assays. In the presence of hydrogen peroxide and HRP, ABTS is oxidized to a radical cation...

A 10 mM (1 mg in 125 μl) solution of caspase-3 inhibitor Q-DEVD-OPh (Cat. No. 1175-1) in DMSO.Alternate Name/Synonyms: Q-D(OMe)-E(OMe)-VD(OMe)-OPhAppearance: LiquidAppearance: 10 mM solution in...

A 10 mM (1 mg in 190 µl) solution of the negative control Q-VE-OPh (Cat. No, 1171-1) for the caspase inhibitor Q-VD-OPh (Cat. No. 1170-1) in DMSO.Alternate Name/Synonyms: Q-Val-Glu-OPh;...

A 10 mM (1 mg in 195 µl) solution of caspase inhibitor Q-VD-OPh (Cat. No, 1170-1) in DMSO.Alternate Name/Synonyms: Q-Val-Asp-OPh; Quinolyl-Val-Asp-OPhAppearance: LiquidAppearance: DMSO (10...

A potent, cell-permeable, and irreversible inhibitor of calpain II (k₂ = 28,900 M⁻¹s⁻¹). Also acts as an inhibitor of cathepsin L (k₂= 680,000 M⁻¹s⁻¹).Alternate Name/Synonyms: Z-LLY-FMK, Calpain...