EZSolution™

RNase A is an endoribonuclease that specifically cleaves the single strand RNA at the phosphodiester bond between the 5’-ribose of a nucleotide and the 3’ OH phosphate group of an adjacent pyrimidine nucleotide. The highest activity is demonstrated with...

Biomolecule/Target: N/ASynonyms: Protease K, Endopeptidase K, Tritirachium alkaline proteinaseAlternates names: Protease K, Endopeptidase K, Tritirachium alkaline proteinaseTaglines: A serine protease which inactivates nucleasesTaglines: USACountry of...

Biomolecule/Target: N/ASynonyms: Serratia marcescens binuclease; unrestricted endonucleaseAlternates names: Serratia marcescens binuclease; unrestricted endonucleaseTaglines: For digestion of DNA and RNATaglines: USACountry of Animal Origin: USANCBI Gene...

BioVision’s EZSolution™ Protein Stabilizer is a very effective BSA alternative. It consists of a proprietary protein expressed in E. coli. The proprietary formulation helps protect proteins and enzymes against heat or chemically-induced environmental...

Propidium iodide (PI) is a nuclear and chromosome counterstain commonly used to detect dead cells in a population. PI binds to double-stranded DNA, but it can only cross the plasma membrane of nonviable cells. When viewed using a fluorescence microscope...

EZSolution™ LDN193189 is a 10.9 mM (5 mg in 1.13 ml) solution of LDN193189 (Cat. No. B3067) in anhydrous DMSO.Alternate Name/Synonyms: 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline; DM-3189Appearance: LiquidAppearance: A 10.9 mM...

Luciferin is a substrate for luciferase. It is oxidised by luciferase to generate light in the presence of ATP. Luciferase is used as a reporter gene linked to a promoter of interest. Luciferin is used to assess the expression of the luciferase gene. It...

A 10 mM (5 mg in 1.34 ml) of the ATP-competitive c-Met kinase inhibitor (Cat. No. B2062) in anhydrous DMSOAlternate Name/Synonyms: PF04217903, 4-[1-(6-Quinolinylmethyl)-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazole-1-ethanolAppearance:...

A 10 mM (5 mg in 888 µl) of the potent inhibitor of FLT kinase, PDGFRβ and c-Kit Tandutinib (Cat. No. 2024) in anhydrous DMSO.Alternate Name/Synonyms: CT53518,...

A 10 mM (5 mg in 1.13 ml) solution of the FLT3 tyrosine kinase inhibitor Crenolanib (Cat. No. 9679) in anhydrous DMSO.Alternate Name/Synonyms: 1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine, ARO 002,...

A 10 mM (5 mg in 922 µl) solution of the dual inhibitor of the tyrosine kinases c-Src and Abl Saracatinib (AZD-0530) (Cat. No. 1582) in anhydrous DMSO.Alternate Name/Synonyms: AZD0530,...

A 10 mM (5 mg in 1.35 ml) of the CDK inhibitor AZD-5438 (Cat. No. B2073) in anhydrous DMSOAlternate Name/Synonyms: 4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)-N-(4-(methylsulfonyl)phenyl)pyrimidin-2-amineAppearance: LiquidAppearance: A 10 mM solution in...

A 10 mM (1 mg in 306 µl) of the JAK inhibitor Peficitinib (Cat. No. B2474) in anhydrous DMSOAlternate Name/Synonyms: ASP015K, JNJ-54781532, 4-(((1R,2r,3S,5s,7s)-5-hydroxyadamantan-2-yl)amino)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide,...

A 10 mM (5 mg in 1.55 ml) of the JAK1 inhibitor PF-04965842 (Cat. No. B2470) in anhydrous DMSOAlternate Name/Synonyms: N-((1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide, PF04965842, AbrocitinibAppearance:...

A 10 mM (5 mg in 1.28 ml) solution of the potent and selective JAK3 inhibitor Decernotinib (VX-509) in anhydrous DMSO.Alternate Name/Synonyms: (R,Z)-2-((2-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)-2-methyl-N-(2,2,2-trifluoroethyl)butanimidic...

INF39 is an irreversible and noncytotoxic NLRP3 inhibitor. It inhibits IL-1β release, caspase activation and pyroptosis in THP-1 cells.Alternate Name/Synonyms: INF 39, Ethyl 2-(2-chlorobenzyl)acrylateAppearance: LiquidAppearance: A 10 mM ( 5 mg in 2.23...

A 10 mM (5 mg in 695 µl) of the potent proteasome inhibitor Carfilzomib (Cat. No. 2385) in anhydrous DMSO.Alternate Name/Synonyms: PR-171; (S)-4-methyl-N-((S)-1-((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)...

A 10 mM (5 mg in 1.0 ml) of the potent EGFR inhibitor AZD-9291 (Osimertinib) (Cat. No. 2674) in anhydrous DMSO.Alternate Name/Synonyms: Mereletinib; Osimertinib;...

A 10 mM (5 mg in 941 µl) of the potent MEK inhibitor Cobimetinib (Cat. No. B1689) in anhydrous DMSO.Alternate Name/Synonyms: [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone; XL518; GDC0973;...

A 10 mM (5 mg in 1.38 ml) of the potent proteasome inhibitor Ixazomib (Cat. No. B2384) in anhydrous DMSO.Alternate Name/Synonyms: MLN-2238; MLN2238; (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acidAppearance: LiquidAppearance: A 10...

A 10 mM (5 mg in 953 µl) of the potent JAK2 inhibitor TG101348 (Fedratinib) in anhydrous DMSO.Alternate Name/Synonyms: N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide; Fedratinib; TG101348;...

A 10 mM (5 mg in 1.31 ml) solution of the potent JAK1 inhibitor ABT-494 (Upadacitinib) in anhydrous DMSO.Alternate Name/Synonyms: (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide;...

A 10 mM (1 mg in 212 µl) of the potent JAK2/FLT3 inhibitor Pacritinib (SB1518) (Cat. No. 2450) in anhydrous DMSO.Alternate Name/Synonyms: SB-1518, SB1518, 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6)...

A 10 mM (5 mg in 1.21 ml) of the JAK1 and JAK2 inhibitor Cyt387 (Momelotinib) (Cat. No. 2316) in anhydrous DMSO.Alternate Name/Synonyms: CYT-11387, Momelotinib, CYT11387, (N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-l)-benzamideAppearance:...

A 10 mM (5 mg in 1064 µl) solution of the potent JAK2 inhibitor LY-2784544 (Gandotinib) (Cat. No. B1914) in anhydrous DMSO.Alternate Name/Synonyms: LY-2784544,...

A 10 mM (5 mg in 1.12 ml) solution of the potent Syk and JAK inhibitor Cerdulatinib (Cat. No. 2803) in anhydrous DMSO.Alternate Name/Synonyms: 4-(cyclopropylamino)-2-[[4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl]amino]-5-pyrimidinecarboxamide, PRT062070,...

A 10 mM (5 mg in 1.18 ml) solution of the potent JAK1 inhibitor Filgotinib (Cat. No. 2871) in anhydrous DMSO.Alternate Name/Synonyms: N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide, GLPG0634,...

A 10 mM (5 mg in 1.35 ml) of the JAK1 and JAK2 inhibitor Baricitinib (Cat. No. 2842) in anhydrous DMSO.Alternate Name/Synonyms: INCB028050, LY-3009104, LY 3009104,...

A 10 mM (5 mg in 1.48 ml) solution of the JAK inhibitor PF-03394197 (Oclacitinib) in anhydrous DMSO.Alternate Name/Synonyms: Oclacitinib, N-Methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamideAppearance:...

A 10 mM (5 mg in 1.60 ml) solution of the potent JAK3 inhibitor CP-690550 (Cat. No. 1622) in anhydrous DMSO.Alternate Name/Synonyms: EZSolution™ Tasocitinib; EZSolution™ Tofacitinib,...

A 10 mM (5 mg in 1.63 ml) solution of the potent JAK inhibitor Ruxolitinib (Cat. No. 2139) in anhydrous DMSO.Alternate Name/Synonyms: NCB18424; βR-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; INC18424; INCB...

A 5 mM ( 1 mg in 520 µl) sterile-filtered solution of the broad spectrum MMP inhibitor GM-6001 (Cat. No. 1799) in anhydrous DMSOAlternate Name/Synonyms: Ilomastat,N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan...

A 10 mM (5 mg in 1.67 ml), sterile-filtered solution of the anticancer agent Gemcitabine Hydrochloride (Cat. No. 1759) in deionized waterAlternate Name/Synonyms: Gemcitabine,Gemcitabine, EZSolution™Appearance: LiquidAppearance: A 10 mM sterile-filtered...

A 10 mM (5 mg in 1.47 ml), sterile-filtered solution of the ferroptosis inhibitor Liproxstatin-1 (Cat. No. B2312) in anhydrous DMSOAlternate Name/Synonyms: Liproxstatin-1, EZSolution™,Liproxstatin-1Appearance: LiquidAppearance: A 10 mM sterile-filtered...

A 10 mM (5 mg in 703 μl), sterile-filtered solution of the PDX1 inducer BRD-7552 (Cat. No. B2258) in anhydrous DMSO.Alternate Name/Synonyms: Methyl [2,3-O-bis(Benzo[1,3]dioxol-5-yl-carbamoyl)]-4-O-(4Appearance: LiquidAppearance: N/AAppearance:...

A 10 mM (5 mg in 1163 μl), sterile-filtered solution of the cAMP analog, 8-Br-cAMP (Cat. No. 1837) in anhydrous DMSO.Alternate Name/Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic 8- bromoadenosine- 3', 5'- monophosphate; 8-...

A 10 mM (5 mg in 1067 μl), sterile-filtered solution of the CBP/EP300 bromodomain inhibitor I-CBP112 (Cat. No. 9405) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1236 μl), sterile-filtered solution of the bromodomain inhibitor Bromosporine (Cat. No. 2652) in anhydrous DMSO.Alternate Name/Synonyms: Ethyl...

A 10 mM (5 mg in 948 μl), sterile-filtered solution of the p38 MAP kinase inhibitor Doramapimod (Cat. No. 1954) in anhydrous DMSO.Alternate Name/Synonyms: 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea;...

A 5 mM (2 mg in 963 μl), sterile-filtered solution of the BET bromodomain inhibitor I-BET151 (Cat. No. 2220) in anhydrous DMSO.Alternate Name/Synonyms:...

A 5 mM (2 mg in 1.15 ml), sterile-filtered solution of the BET bromodomain inhibitor PFI-1 (Cat. No. 2203) in anhydrous DMSO.Alternate Name/Synonyms: 2-​Methoxy-​N-​(3-​methyl-​2-​oxo-​1,​2,​3,​4-​tetrahydroquinazolin-​6-​yl)benzenesulfonamideAppearance:...

A 10 mM (5 mg in 1.82 ml), sterile-filtered solution of the phosphodiesterase-4 (PDE4) inhibitor Rolipram (Cat. No. 2010) in anhydrous DMSO.Alternate Name/Synonyms: 4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-oneAppearance: LiquidAppearance:...

A 10 mM (5 mg in 1.53 ml), sterile-filtered solution of the Rho Kinase (ROCK) inhibitor Fasudil (Cat. No.1787) in water.Alternate Name/Synonyms: (1-(5-Isoquinolinesulfonyl)homopiperazine, Monohydrochloride Salt; HA-1077, Monohydrochloride;...

A 10 mM (5 mg in 977 μl), sterile-filtered solution of the gamma- secretase inhibitor BMS-299897 (Cat. No. 9606) in anhydrous DMSO.Alternate Name/Synonyms: (R)-4-(2-(1-(4-chloro-N-(2,5-difluorophenyl)phenylsulfonamido)ethyl)-5-fluorophenyl)butanoic...

A 10 mM (5 mg in 1.43 ml), sterile-filtered solution of the RAR agonist TTNPB (Cat. No. 2776) in anhydrous DMSO.Alternate Name/Synonyms: 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid; Ro 13-7410Appearance:...

A 10 mM (5 mg in 2.37 ml), sterile-filtered solution of the STAT3 activation inhibitor Stattic (Cat. No. 2625) in anhydrous DMSO.Alternate Name/Synonyms: 6-​Nitro-​1,​1-​dioxide-​benzo[b]thiophene; Stat3 Inhibitor VAppearance: LiquidAppearance:...

A 10 mM (5 mg in 2.13 ml), sterile-filtered solution of the neurogenesis promoter (Cat. No. 2563) in anhydrous DMSO.Alternate Name/Synonyms: N-cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamideAppearance: LiquidAppearance: N/AAppearance:...

A 5 mM (2.45 mg in 1 ml), sterile-filtered solution of the Smo agonist SAG (Cat. No. 1939) in anhydrous DMSO.Alternate Name/Synonyms: N-Methyl-N′-(3-pyridinylbenzyl)-N′-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexaneAppearance:...

A 10 mM (5.0 mg in 1.50 ml), sterile-filtered solution of the DNA methyltransferase (DNMT) inhibitor RG-108 (Cat. No. 1679) in anhydrous DMSO.Alternate Name/Synonyms: N-Phthalyl-L-tryptophanAppearance: LiquidAppearance: N/AAppearance:...

A 10 mM (5.0 mg in 1.57 ml), sterile-filtered solution of the GSK-3β inhibitor TWS-119 (Cat. No. 1655) in anhydrous DMSO.Alternate Name/Synonyms: 3-[[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenolAppearance: LiquidAppearance:...

A 10 mM (5.0 mg in 960 μl), sterile-filtered solution of the Smoothened (Smo) Receptor Agonist Purmorphamine (Cat. No. 1672) in anhydrous DMSO.Alternate Name/Synonyms: 9-cyclohexyl-N-(4-morpholin-4-ylphenyl)-2-naphthalen-1-yloxypurin-6-amineAppearance:...

A 10 mM (5.0 mg in 1.50 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer SCR7 Pyrazine (Cat. No. B1119) in anhydrous DMSO.Alternate Name/Synonyms: 2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinoneAppearance:...

A 10 mM (5.0 mg in 954 μl), sterile-filtered solution of the HDR (homology-directed repair) enhancer RS-1 (Cat. No. B1118) in anhydrous DMSO.Alternate Name/Synonyms: 4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamideAppearance:...

A 5 mM (5.0 mg in 2.42 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer NU-7441 (Cat. No. B1117) in anhydrous DMSO.Alternate Name/Synonyms: 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one; KU-57788Appearance:...

A 10 mM (5.0 mg in 1.66 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer Nocodazole (Cat. No. 2185) in anhydrous DMSO.Alternate Name/Synonyms: 5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbonic acid, methyl esterAppearance:...

A 10 mM (5.0 mg in 855 μl), sterile-filtered solution of the HDR (homology-directed repair) enhancer L-755,507 (Cat. No. B1116) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5.0 mg in 1.78 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer Brefeldin A (Cat. No. 1560) in anhydrous DMSO.Alternate Name/Synonyms: Ascotoxin, BFA, Cyanein, Decumbin,...

SYBR Green I is a highly sensitive fluorescent DNA binding stain for staining of double stranded DNA (dsDNA) or oligonucleotides in agarose or polyacrylamide gels.Alternate Name/Synonyms: EZSolution™ SYBR Green I; Sybr green;...

A solution (20 mg/ml) of the antibiotic Phleomycin (Cat. No. 2724) in deionized water. Sterile-filtered.Alternate Name/Synonyms:...

A 10 mM (5.06 mg in 1 ml) solution of the neuroprotective agent P7C3-A20 (Cat. No. 2850) in anhydrous DMSO.Alternate Name/Synonyms: N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-3-methoxyanilineAppearance: LiquidAppearance: A 10 mM solution in...

A 10 mM (1 mg in 162 μl) solution of the p53-MDM2 interaction inhibitor RG7388 (Cat. No. 2577) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (10 mg in 3.86 ml) solution of the antitumor and anti-inflammatory agent (R, S)-Lenalidomide (Cat. No. 1862) in anhydrous DMSO.Alternate Name/Synonyms: (R,S)-3-(4-amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dioneAppearance: LiquidAppearance: A 10...

A 10 mM (1 mg in 183 μl) of the antitumor agent Erastin (Cat. No. 2231) in anhydrous DMSO.Alternate Name/Synonyms: 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-QuinazolinoneAppearance: LiquidAppearance: A 10 mM...

A 10 mM (3.83 mg in 1 ml) of RIPK3 (receptor-interacting protein kinase-3) inhibitor (Cat. No. 2673) in anhydrous DMSO.Alternate Name/Synonyms: N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine; GSK-872Appearance: LiquidAppearance: A 10 mM...

A 10 mM (10 mg in 2.17 ml), sterile-filtered solution of the necroptosis inhibitor Necrosulfonamide (Cat. No. 9635) in anhydrous DMSO.Alternate Name/Synonyms: (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide;...

A 10 mM (5.74 mg in 1 ml), sterile-filtered solution of the GSK-3β inhibitor CHIR99021 trihydrochloride (Cat. No. B1199) in anhydrous DMSOAlternate Name/Synonyms:...

EZSolution(TM) Triacsicn C, is an Inhibitor of acyl-CoA synthetase (IC₅₀ = 6.3 μM in Raji cells). Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft...

A 10 mM (5 mg in 1072 µl) of the terpenoid lactone Nimbolide (Cat. No. 1891) in anhydrous DMSO.Alternate Name/Synonyms:...

A 10 mM (5 mg in 1294 µl) of the rapid apoptosis inducer Raptinal (Cat. No. 9626) in anhydrous DMSO.Alternate Name/Synonyms: 9H, 9’H-[9,9’-bifluorene]-9,9’-dicarbaldehydeAppearance: LiquidAppearance: A 10 mM solution in DMSOAppearance: N/AAppearance:...

A 10 mM (5 mg in 1807 µl) of PPARγ antagonist GW9662 (Cat. No. 1697) in anhydrous DMSO.Alternate Name/Synonyms: 2-Chloro-5-nitrobenzanilideAppearance: LiquidAppearance: A 10 mM solution in DMSOAppearance: 22978-25-2Appearance: YesPeptide sequence:...

A 10 mM (5 mg in 1403 µl) of PPARγ agonist Pioglitazone (Cat. No. 1877) in anhydrous DMSO.Alternate Name/Synonyms: 5-​[[4-​[2-​(5-​ethyl-​2-​pyridinyl)ethoxy]phenyl]methyl]-​2,​4-​thiazolidinedioneAppearance: LiquidAppearance: A 10 mM solution in...

A 10 mM (5 mg in 2270 µl) of the JNK inhibitor SP600125 (Cat. No.1669) in anhydrous DMSO.Alternate Name/Synonyms: Anthra[1-9-cd]pyrazol-6(2H)-oneAppearance: LiquidAppearance: 11 mM solution in anhydrous DMSOAppearance: 129-56-6Appearance: YesPeptide...

A 10 mM (1 mg in 226 µl) of PKC inhibitor Gö 6983 (Cat. No.9539) in anhydrous DMSO.Alternate Name/Synonyms: 3-[1-[3-(dimethylamino)propyl]-5-methoxyindol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dioneAppearance: LiquidAppearance: 10 mM solution in anhydrous...

A 10 mM (1 mg in 171 µl) of Hsp90 inhibitor 17-AAG (Cat. No.1774) in anhydrous DMSO.Alternate Name/Synonyms: Telatinib; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)geldanamycin; TanespimycinAppearance: LiquidAppearance: A 10 mM solution in...

A 10 mM (1 mg in 166 µl) of heme-independent soluble guanylyl cyclase activator BAY 58-2667 hydrochloride (Cat. No. 2027) in anhydrous DMSO.Alternate Name/Synonyms: 4-((4-carboxybutyl)(2-((4-phenethylbenzol)- oxy)phenethyl)amino)methyl(benzoic) acid;...

A 10 mM (1 mg in 264 µl) of potent Wnt signaling pathway inhibitor (Cat. No. 2063) in anhydrous DMSO.Alternate Name/Synonyms: 2-(4-(2-Methylpyridin-4-yl)phenyl)-N-4-(pyridin-3-yl)phenyl)acetamideAppearance: LiquidAppearance: A 10 mM solution in...

A 10 mM (5 mg in 2098 µl) of the VEGFR kinase inhibitor SU-5416 (Cat. No. 9491) in anhydrous DMSO.Alternate Name/Synonyms: 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one; SemaxinibAppearance: LiquidAppearance: A 10 mM solution in...

A 10 mM (5 mg in 1456 µl) of the ALK5 inhibitor SB-525334 (Cat. No. 2880) in anhydrous DMSO.Alternate Name/Synonyms: 6-[2-(1,1-Dimethylethyl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-4-yl]quinoxalineAppearance: LiquidAppearance: A 10 mM solution in...

A 10 mM (5 mg in 1653 µl) of the PARP inhibitor DPQ (Cat. No. 1899) in anhydrous DMSO.Alternate Name/Synonyms: 3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinoneAppearance: LiquidAppearance: A 10 mM solution in anhydrous DMSOAppearance:...

A sterile-filtered solution (50 mg/ml) of the antibiotic G-418 sulfate (Cat. No. 1557) in water.Alternate Name/Synonyms: Antibiotic G418, G418, geneticin, EZSolution™ GeneticinAppearance: LiquidAppearance: 50 mg/ml in waterAppearance:...

MAFP is a potent inhibitor of fatty acid amide hydrolase (FAAH) (IC₅₀ = 2.5 nM). MAFP also binds to the CB1 receptor in rat brain membrane preparations (IC₅₀ = 20 nM). MAFP also acts as a selective, active-site directed, irreversible inhibitor of cPLA2...

A 10 mM (10 mg in 1080 µl) of the EGFR inhibitor Lapatinib ditosylate (Cat. No.1624) in anhydrous DMSO.Alternate Name/Synonyms: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine...

A 10 mM (5 mg in 1038 µl) of the HMG-CoA inhibitor Rosuvastatin (Cat. No. 1955) in anhydrous DMSO.Alternate Name/Synonyms: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic...

A sterile-filtered aqueous solution (10 mg/ml) of the antibiotic Blasticidin HCl (Cat.No. 1859) in HEPES (20 mM), pH 7.5.Alternate Name/Synonyms: Blasticidine SAppearance: LiquidAppearance: 10 mg/ml in 20 mM HEPES, pH 7.5.Appearance: 3513-03-9 ...

5-Fluoroorotic Acid (5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) decarboxylase. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5’-phosphate...

DAF-2 diacetate is a cell-permeable derivative of DAF-2 (Cat. No. 2752) and a very useful indicator of nitric oxide (NO). Upon entry into the cell, DAF-2 diacetate is converted into the less cell-permeable DAF-2 by cellular esterases thus preventing loss...

DAF-2 is a highly sensitive fluorescent indicator commonly used for the detection of nitric oxide (NO). It reacts with NO in the presence of oxygen to yield the highly fluorescent triazolofluorescein (DAF-2T). Fluorescence is monitored using excitation...

A solution (1 mg/ml) of the fluorescent DNA dye 7-aminoactinomycin D (7-AAD) (Cat. No.2725) in anhydrous DMSO.Alternate Name/Synonyms: 7-AAD; NSC-239759;...

A 10 mM (5 mg in 1156 µl) solution of γ-secretase inhibitor DAPT (Cat. No.1855) in anhydrous DMSO.Alternate Name/Synonyms: N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl EsterAppearance: LiquidAppearance: A 10 mM solution in...

A 10 mM (5 mg in 1218 µl) solution of adenylyl cyclase activator Forskolin (Cat. No. 1531) in anhydrous DMSO.Alternate Name/Synonyms: Coleonol, Colforsin, 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-oneAppearance: LiquidAppearance: A 10 mM...

A 10 mM (5 mg in 1019 µl) solution of the HMTase inhibitor BIX01294 (Cat. No. 1678) in anhydrous DMSO.Alternate Name/Synonyms: 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamineAppearance:...

A 10 mM (1 mg in 233 µl) of the stem cell fate modulator StemRegenin 1 (Cat. No. 2642) in anhydrous DMSOAlternate Name/Synonyms: 4-(2-((2-Benzo[b]thiphen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol; SR1Appearance: LiquidAppearance: N/AAppearance:...

A 10 mM (5 mg in 1740 µl) of the ALK5 inhibitor RepSox (Cat. No. 1894) in anhydrous DMSO.Alternate Name/Synonyms: 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E-616452Appearance: LiquidAppearance: N/AAppearance: 446859-33-2Appearance:...

A 10 mM (1 mg in 231 µl) of the ROCK inhibitor GSK429286A (Cat. No. 2637) in anhydrous DMSO.Alternate Name/Synonyms: 4-[4-(Trifluoromethyl)phenyl]-N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide; GSK429286Appearance:...

A 10 mM (1 mg in 206 µl) of the GSK-3 inhibitor CHIR-98014 (Cat. No. 2595) in anhydrous DMSO.Alternate Name/Synonyms: 6-N-[2-[[4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine; CT 98014Appearance:...

A 10 mM (5 mg in 1744 µl) of the PDK1 activator PS48 (Cat. No. 1869) in anhydrous DMSO.Alternate Name/Synonyms: (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic acidAppearance: LiquidAppearance: A 10 mM solution in DMSOAppearance: 1180676-32-7Appearance:...

A sterile-filtered solution (50 mg/ml) of the antibiotic Hygromycin B (Cat. No. 2589) in PBS buffer.Alternate Name/Synonyms:...

A small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits lipopolysaccharide (LPS)-induced TNF production in mice, but not...

Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1,

Cell-permeable. A potent, selective , reversible and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM in the presence of 5 µM ATP and no AMP). Does not affect the activity on several structurally related kinases including...